THE PARTIAL DEHYDROGENATION OF OLEANOLIC ACID
نویسندگان
چکیده
منابع مشابه
Oleanolic acid ethanol monosolvate
CRYSTALS OF THE TITLE COMPOUND (SYSTEMATIC NAME: 3β-hy-droxy-olean-12-en-28-oic acid ethanol monosolvate), C(30)H(48)O(3)·C(2)H(5)OH, were obtained from unsuccessful co-crystallization trials. The asymmetric unit contains two symmetry-independent oleanolic acid mol-ecules, as well as two ethanol solvent mol-ecules. Inter-molecular O-H⋯O hydrogen bonds stabilize the crystal packing. In the olean...
متن کاملPharmacology of oleanolic acid and ursolic acid.
Oleanolic acid and ursolic acid are triterpenoid compounds that exist widely in food, medicinal herbs and other plants. This review summarizes the pharmacological studies on these two triterpenoids. Both oleanolic acid and ursolic acid are effective in protecting against chemically induced liver injury in laboratory animals. Oleanolic acid has been marketed in China as an oral drug for human li...
متن کاملEnhancement of Platelet Aggregation by Ursolic Acid and Oleanolic Acid
The pentacyclic triterpenoid ursolic acid (UA) and its isomer oleanolic acid (OA) are ubiquitous in food and plant medicine, and thus are easily exposed to the population through natural contact or intentional use. Although they have diverse health benefits, reported cardiovascular protective activity is contentious. In this study, the effect of UA and OA on platelet aggregation was examined on...
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چکیده ندارد.
15 صفحه اولComparison of the inhibition capability of oleanolic acid and betulinic acid towards drug-metabolizing enzymes.
BACKGROUND Human UDP-glucuronosyltransferases (UGTs) are important membrane proteins located in endoplasmic reticulum, and play important roles in metabolism of a variety of endogenous and exogenous compounds. AIMS To determine the influence of subtle difference in the structure of oleanolic acid and betulinic acid towards the inhibition towards the activity of UGT isoforms. METHODS In vitr...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1932
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)76272-8